• PERSONAL HISTORY
  • QUESTIONNAIRE
  • FAMILY HISTORY
  • YOUR RESULTS
  • FAQs

Tyrer-Cuzick Risk Assessment Calculator

This risk calculator asks questions about your personal and family history to determine your lifetime risk probability of developing breast cancer compared with the age-adjusted U.S. population average probability of developing breast cancer. The purpose of this tool is simply to inform you. Please consult with your healthcare provider should you have any questions about your risk of developing breast cancer or for guidance on options for breast cancer screening or genetic counseling.

The Tyrer-Cuzick model is not intended to assess the risk of women who have already been diagnosed with breast cancer.

Attention Clinical Users: This free calculator is for non-commercial, including non-clinical use. Such use would require a license. Learn more about our clinical risk assessment software.

Assess Breast Cancer Risk

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Tyrer-Cuzick Risk Model (IBIS Breast Cancer Risk Evaluation Tool)

This calculator uses the Tyrer-Cuzick or IBIS v8 risk assessment model.

*Note: Competing mortality is turned "ON" for consistency. Competing mortality is the possibility that one may die from causes other than breast cancer.

*Disclaimer: This information is not intended as a substitute for professional healthcare and is not intended to replace the evaluation of a healthcare professional. Always consult with a healthcare provider for advice concerning your health. Only your healthcare provider can determine if you have breast cancer. Do not disregard professional medical advice or delay seeking advice or treatment because of something you have read here.

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Note: HRT includes estrogen-only or combined estrogen and progesterone but does not include hormonal birth control.

If you have had a breast biopsy and are unsure about which result to select below, this information should be displayed on your pathology report.

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If you are unsure about which breast density category you fall under, this information should be displayed on your last mammography report. If you have not had a mammogram in the past, or are unsure about which breast density category you fall under, select the "I don't know" option below.

cancer historyMother

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Note: Please leave your response to this question as blank if you do not know or are unsure.

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cancer historyFather

Note: Please leave your response to this question as blank if you do not know or are unsure.

cancer historySisters

cancer historyDaughters

cancer historyBrother(s)

Do any of your brothers have a daughter with a history of breast or ovarian cancer?
Add Niece

cancer historyPaternal Grandmother

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cancer historyPaternal Aunts

cancer historyPaternal Half Sisters

cancer historyPaternal Uncle's Daughters

cancer historyMaternal Grandmother

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cancer historyMaternal Aunts

cancer historyMaternal Half Sisters

cancer historyMaternal Uncle's Daughters

Your Results

The results below are based on the IBIS risk assessment model, also known as the Tyrer-Cuzick (v8) risk assessment model. These results show your lifetime risk of developing breast cancer compared to the age-adjusted U.S. population average.

Your Breast Cancer Risk Assessment Score

Based on the information provided, your estimated lifetime risk for developing invasive breast cancer is . The U.S. population's average lifetime risk is for women of the same age.

If your lifetime risk is 20% or greater: you are at high risk for developing breast cancer. Yearly MRI is recommended in addition to a mammogram. If MRI is not possible, a contrast-enhanced mammogram (CEM) or molecular breast imaging (MBI) is recommended. If these tests are not possible, an ultrasound should be considered.

If your lifetime risk is less than 20% and you have dense breasts: dense breasts make cancer more difficult to see on a mammogram. Consider yearly MRI in addition to your yearly mammogram as MRI finds more cancers than a mammogram alone in dense breasts. If MRI is not possible, consider a contrast-enhanced mammogram (CEM) or molecular breast imaging (MBI). If these tests are not possible, consider ultrasound.

If your lifetime risk is less than 20% and you do not have dense breasts, it is recommended that you follow protocol for women at average risk for breast cancer (and without dense breasts). A yearly mammogram beginning at age 40 is recommended for women at average risk.

Should you have any questions about the results you see here, recommendations for screening tests, or about your personal breast cancer screening journey, please contact your healthcare provider (primary care physician or OB GYN).

Disclaimer: This information is not intended as a substitute for professional healthcare or to replace a healthcare professional's evaluation. Always consult with a healthcare provider for advice concerning your health. Only your healthcare provider can determine if you have breast cancer. Do not disregard professional medical advice or delay seeking advice or treatment because of something you have read here.

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Frequently Asked Questions.

The Tyrer-Cuzick risk calculator can help determine the possibility of developing breast cancer during your lifetime. The purpose of this tool is to help you become better informed and assist you in how you should proceed with your breast cancer screening journey.

Q1. What is the Tyrer-Cuzick risk model and how is it used for breast cancer risk assessment?

The Tyrer-Cuzick model, sometimes referred to as the IBIS tool, provides a risk score that estimates the likelihood of a woman developing breast cancer over the course of her lifetime . The risk score is calculated using a variety of risk factors that include personal health history, as well as family health history. The score is typically expressed as a percentage.

Q2. What are the risk factors used to calculate a Tyrer-Cuzick risk score?

The major risk factors that determine a Tyrer-Cusick risk score are:

  • Age
  • Height
  • Weight
  • Age at first period
  • Age at first child birth
  • Menopause stage
  • Age at menopause
  • History of hormone use
  • Personal BRCA genetic test results (BRCA1 & BRCA 2)
  • Personal history of atypical breast biopsies (i.e. ADH, ALH, LCIS)
  • Personal history of ovarian cancer
  • Breast tissue density
  • Ashkenazi Jewish inheritance
  • Number of sisters
  • Number of daughters
  • Number of half sisters
  • Number of aunts
  • Family history of breast cancer
  • Age at which family history of breast cancer was diagnosed
  • Family history of breast cancer diagnosed in one breast or both breasts
  • Family history of ovarian cancer
  • Age at which family history of ovarian cancer was diagnosed
  • Family history of BRCA genetic test results

Q3. What does it mean to have dense breast tissue, and why does it matter for my Tyrer-Cuzick risk score?

Breast cancer research and advances in risk assessment have shown that having dense breasts is a contributing factor in determining a woman’s risk of breast cancer. Dense breast tissue refers to the appearance of breast tissue on a mammogram and the makeup of supportive and fatty tissue in the breast. The more fatty tissue, the less dense the breast is. Dense breasts are common and can be caused by simply being younger, having a lower body mass index, or taking hormone therapy for menopause; researchers are still studying why some women have dense breasts and others do not.

Non-dense breast tissue appears dark and transparent, whereas dense breast tissue appears as a solid white area on a mammogram; this solid white area can make it hard for radiologists to accurately analyze the image with a mammogram alone. Therefore, your healthcare provider may recommend supplemental imaging, like a breast ultrasound or breast MRI, to increase the likelihood of finding cancer. Having dense breast tissue alone is not a cause for concern. You should speak with your healthcare provider about your breast tissue density and how it affects your risk status.

Q4. Why is it important for me to know my risk score?

Risk assessment can help breast centers tailor screening and follow up recommendations to ensure you are receiving the care you need. Risk assessment identifies women who are candidates for additional imaging, genetic counseling, genetic testing, and/or other specialized recommendations.

Q5. What is considered a high risk score for Tyrer-Cuzick?

Some facilities may have different guidelines, so you should check with your healthcare provider, but generally:

  • Less than 15% is considered average risk
  • Between 15-19% is considered intermediate risk
  • 20% or greater is considered high risk

Q6. Are there other risk models like the Tyrer-Cuzick model?

Yes, there are other risk models such as Gail/NCI, BRCAPRO, Claus, BCSC and more; however, Tyrer-Cuzick has been widely accepted as the most comprehensive risk model due to more detailed data collection. Your healthcare provider may use one or more of the models listed above together.

Q7. How can I have my risk score calculated?

While risk calculators and other tools exist online, it is best to speak with your healthcare provider about having your risk score calculated. Learning you are high risk from an online calculator without guidance from your healthcare provider may cause unnecessary anxiety.

Q8. I am in the high risk category – does this mean I will definitely develop breast cancer?

No, being high risk just means that when statistically compared to other women, your chances are higher, sometimes only slightly higher. It is completely understandable to be concerned about your high risk status, but early detection is your best tool against breast cancer. By identifying your risk, your healthcare providers can provide you with a personalized screening plan and/or risk reduction options.

Q9. I am in the high risk category – Is there anything I can do to reduce my risk of being diagnosed with breast cancer?

You should speak with your healthcare provider about your specific circumstances to determine if there is anything you can do to lower your risk. In some cases, your healthcare provider may recommend lifestyle changes, and in higher risk cases, there are risk-reducing drugs and interventional surgery options. It is important, however, that your healthcare provider makes the appropriate recommendations.

Q10. I have already been diagnosed with breast cancer. Does the Tyrer-Cuzick risk model apply to me?

No, the Tyrer-Cuzick risk model does not apply to those already diagnosed with breast cancer and those over the age of 85.

Q11. Are there additional resources online to learn more about breast cancer risk assessment?

While your healthcare provider and imaging providers are the best resources, here are sites that can provide you with more information until you speak with your healthcare provider:

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Note: Every reported issue that is logged is thoroughly investigated and reviewed by our team. We review reported issues in the order in which they are received. Please do not expect a response from our team related to your reported issue. We will address any and all reported issues that will improve the quality of our online risk calculator.

Report an Issue

Note: Every reported issue that is logged is thoroughly investigated and reviewed by our team. We review reported issues in the order in which they are received. Please do not expect a response from our team related to your reported issue. We will address any and all reported issues that will improve the quality of our online risk calculator.

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